Thymidine Diphosphate 4-Acetamido-4,6-dideoxyhexoses

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Thymidine Diphosphate 4-acetamido-4, 6-dideoxyhexoses. I. Enzymatic Synthesis by Strains of Escherichia Coli.

Several thymidine diphosphate sugar compounds have been isolated from Escherichia coli strains and other microorganisms. TDP-X, isolated from E. coli strain Y-10 by Strominger and Scott (1) and from other strains of E. coli (2) and TDP-X2 isolated from E. coli strain B, by Okazaki, Okazaki, and Kuriki (3) are unusual acetamido sugar-containing nucleotides (4). The sugars are 4-acetamido-4,6-did...

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Thymidine diphosphate mannose and thymidine diphosphate rhamnose in Streptomyces grieus.

Moflwain, H. (1937). J. chem. Soc. p. 1704. Mahler, H. R., Tomisek, A. & Huennekens, F. M. (1953). Exp. Cell Res. 4, 208. Margoliash, E. (1954). Biochem. J. 56, 529. Meyerhof, 0. (1933). Nature, Lond., 132, 337. Molinari, R. & Lara, F. J. S. (1960). Biochem. J. 75, 57. Nemeth, A. M., Russell, C. S. & Shemin, D. (1957). J. biol. Chem. 229, 415. Neuberg, 0. (1913). Biochem. Z. 49, 502. Nygaard, A...

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Enzymatic synthesis of cytidine diphosphate 3,6-dideoxyhexoses. 3. Cytidine diphosphate D-glucose oxidoreductase.

A procedure is described for the purification of CDP-Dglucose oxidoreductase which catalyzes formation of CDP-4keto-6-deoxy-D-glucose and for enzymes El and ES which catalyze the further reduction to CDP-4-keto-3,6-dideoxy-Dglucose. All three enzymes have been purified to homogeneity as judged by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate. CDP-D-glucose oxidore...

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The enzymatic synthesis of thymidine diphosphate glucose and its conversion to thymidine diphosphate rhamnose.

. Studies from several laboratories have shown that labeled glucose is converted to B-deoxy hexoses without randomization of the label when microorganisms are grown on n-glucose-l-C14 or n-glucose-MY4 as the sole source of carbohydrate (l-3). Evidence of this type has been interpreted to indicate a conversion of the intact hexose moiety to the deoxy compound without scission of the hexose carbo...

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Loop dynamics of thymidine diphosphate-rhamnose

30-O-methyltransferase (CalS11), an enzyme in calicheamicin biosynthesis Lu Han, Shanteri Singh, Jon S. Thorson, and George N. Phillips, Jr. Biosciences at Rice, Rice University, Houston, Texas 77005, USA Center for Pharmaceutical Research and Innovation, Pharmaceutical Sciences, University of Kentucky College of Pharmacy, Lexington, Kentucky 40536-0596, USA Chemistry Department, Rice Universit...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1971

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)62296-3